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Temporal dynamics of the host molecular responses underlying severe COVID-19 progression and disease resolution
Ong EZ, Kalimuddin S, Chia WC, Ooi SH, Koh CW, Tan HC, Zhang SL, Low JG, Ooi EE, Chan KR. EBioMedicine. PubMed ID: 33691247
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SINGHEALTH DUKE-NUS RESEARCH TEAM AWARD 2021
Defining the adaptive immune components that protect against COVID-19
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Safety and efficacy of a therapeutic anti-yellow fever virus human antibody
Low JG, Ng JHJ, Ong EZ, Kalimuddin S, Wijaya L, Chan YFZ, Ng DHL, Tan HC, Baglody A, Chionh YH, Lee DCP, Budigi Y, Sasisekharan R, Ooi EE. N Engl J Med. PubMed ID: 32726531
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A non-structural 1 protein G53D substituition attenuates a clinically tested live dengue vaccine
Choy MC, Ng DHL, Siriphanitchakorn T, Ng WC, Sundstrom KB, Tan HC, Zhang ZL, Chan KWK, Manuel M, Kini RM, Chan KR, Vasudevan SG, Ooi EE. Cell Reports. PubMed ID: 32402284
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A Dynamic Immune Response Shapes COVID-19 Progression
Ong EZ, Chan YFZ, Leong WY, Lee NMY, Kalimuddin S, Haja Mohideen SM, Chan KS, Tan AT, Bertoletti A, Ooi EE, Low JGH. Cell Host Microbe. PubMed ID: 32359396
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SINGAPOREAN OF THE YEAR 2020
OOI ENG EONG The Straits Times Singaporean of the Year Award (Front-line fighters against Covid-19) and The Straits Times Asians of the Year Award
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Antibody-dependent dengue virus entry modulates cell intrinsic responses for enhanced infection
Chan CYY, John JZH, Gan ES, Ong EZ, Zhang SL, Tan HC, Chai X, Ghosh S, Ooi EE, Chan KR. mSphere. PubMed ID: 31533998
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Metabolic perturbations and cellular stress underpin susceptibility to symptomatic live attenuated yellow fever infection
Chan KR, Gan ES, Chan CY, Liang C, Low JZ, Zhang SL, Ong EZ, Bhatta A, Wijaya L, Lee YH, Low JG, Ooi EEE. Nat Med. PubMed ID: 31308506
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Structure mapping of dengue and Zika viruses reveals functional long-range interactions
Huber RF, Lim XN, Ng WC, Sim AYL, Poh HX, Shen Y, Lim SY, Sundstrom KB, Sun X, Aw JG, Too HK, Boey PH, Wilm A, Chawla T, Choy MM, Jiang L, Sessions PF, Loh XJ, Alonso S, Hibberd M, Nagarajan N, Ooi EE, Bond PJ, Sessions OM, Wan Y. Nature Communications. PubMed ID:…