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Neutralizing antibody titers do not predict T cell response to live-attenuated orthoflaviviral vaccination in humans
Justin S.G. Ooi, Noor Zayanah Hamis, Hwee Cheng Tan, Jia Xin Yee, Valerie S.Y. Chew, Joey Ming Er Lim, Eugenia Z. Ong, Kuan Rong Chan, Laura Rivino, Jenny G. Low, Eng Eong Ooi, Shirin Kalimuddin. Vaccine. PubMed ID: 41880822
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Vaccine-induced T cell responses control Orthoflavivirus challenge infection without neutralizing antibodies in humans
Kalimuddin S, Tham CYL, Chan YFZ, Hang SK, Kunasegaran K, Chia A, Chan CYY, Ng DHL, Sim JXY, Tan HC, Syenina A, Ngoh AQ, Hamis NZ, Chew V, Leong YS, Yee JX, Low JG, Chan KR, Ong EZ, Bertoletti A, Ooi EE. Nat Microbiol. PubMed ID: 39794472
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ASO1-adjuvanted vaccine alters baseline correlates of T cell response to varicella zoster virus in older adults
Chan CCY, Ooi JSG, Koh CWT, Ong EZ, Tham CYL, Yee JX, Chew VSY, Cheung YB, Ooi EE, Low JG, Chan KR. Vaccine. PubMed ID: 40592255
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Glycans on non-structural protein 1 prevent premature T-cell mediated dengue virus clearance
Idris F, Ooi JSG, Ting DHR, Tan ETX, Wan C, Benke PI, Marzinek JK, Copping JM, Li QH, Ng LY, Lim SY, Walsh I, Allison JR, Bond PJ, Torta F, Nguyen-Khuong T, Chan KR, Alonso S. EMBO Mol Med. PubMed ID: 38689059
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Minding the “T”s beyond the “B”s: Shaping vaccines for future pandemics
Kalimuddin S, Ooi EE. PLoS Biol. PubMed ID: 37934720
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Adverse effects following anti-COVID-19 vaccination with mRNA-based BNT162b2 are alleviated by altering the route of administration and correlate with baseline enrichment of T and NK cell genes
Syenina A, Gan ES, Toh JZN, de Alwis, R, Lin LZ, Tham CYL, Yee JX, Leong YS, Sam H, Cheong C, The YE, Wee ILE, Ng DHL, Chan KR, Sim JXY, Kalimuddin S, Ong EZ, Low JG, Ooi EE. Plos Biol. PubMed ID: 35639676
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Early T cell and binding antibody responses are associated with Covid-19 RNA vaccine efficacy onset
Kalimuddin S, Tham CYL, Qui M, De Alwis R, Sim JXY, Lim JME, Tan HC, Syenina A, Zhang SL, Le Bert N, Tan AT, Leong YS, Yee JX, Ong EZ, Ooi EE, Bertoletti A, Low JG. Med. PubMed ID: 33851143