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Reduced dengue virus pre-membrane protein-HMGB1 interaction activates host cell transcription to attenuate infection
Siriphanitchakorn T, Ooi JSG, Ng WC, Tan HC, Zhang SL, Ng DHL, Yap X, Yee JX, Zheng Q, Tan YT, Ong EZ, Chan KR, Choy MM, Ooi EE. NPJ Vaccines. PubMed ID: 41702930
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Vaccine-induced T cell responses control Orthoflavivirus challenge infection without neutralizing antibodies in humans
Kalimuddin S, Tham CYL, Chan YFZ, Hang SK, Kunasegaran K, Chia A, Chan CYY, Ng DHL, Sim JXY, Tan HC, Syenina A, Ngoh AQ, Hamis NZ, Chew V, Leong YS, Yee JX, Low JG, Chan KR, Ong EZ, Bertoletti A, Ooi EE. Nat Microbiol. PubMed ID: 39794472
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ASO1-adjuvanted vaccine alters baseline correlates of T cell response to varicella zoster virus in older adults
Chan CCY, Ooi JSG, Koh CWT, Ong EZ, Tham CYL, Yee JX, Chew VSY, Cheung YB, Ooi EE, Low JG, Chan KR. Vaccine. PubMed ID: 40592255
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IgG, IgM and nonstructural protein 1 response profiles after receipt of tetravalent dengue vaccine TAK-003 in a phase 2 randomized controlled trial
Low JG, Oh HM, Leo YS, Kalimuddin S, Wijaya L, Pang J, Lee TH, Moss KJ, Brose M, Tricou V. Am J Trop Med Hyg. PubMed ID: 38806045
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Electron transport chain capacity expands yellow fever vaccine immunogenicity
Mok DZ, Tng DJ, Yee JX, Chew VS, Tham CY, Ooi JS, Tan HC, Zhang SL, Lin LZ, Ng WC, Jeeva LL, Murugayee R, Goh KK, Lim TP, Cui L, Cheung YB, Ong EZ, Chan KR, Ooi EE, Low JG. EMBO Mol Med. PubMed ID: 38745062
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Correlates of protection against symptomatic SARS-CoV-2 in vaccinated children
Zhong Y, Kang AYH, Tay CJX, Li HE, Elyana N, Tan CW, Yap WC, Lim JME, Le Bert N, Chan KR, Ong EZ, Low JG, Shek LP, Tham EH, Ooi EE. Nat Med. PubMed ID: 38689059
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Lessons for dengue vaccines from a human challenge study
Ooi EE, Kalimuddin S. Lancet Infect Dis. PubMed ID: 38679034
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Insights into dengue immunity from vaccine trials
Ooi EE, Kalimuddin S. Sci Transl Med. PubMed ID: 37437017
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Minding the “T”s beyond the “B”s: Shaping vaccines for future pandemics
Kalimuddin S, Ooi EE. PLoS Biol. PubMed ID: 37934720
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RNase2 is a possible trigger of acute-on-chronic inflammation leading to mRNA vaccine-associated cardiac complication
Ong EZ, Koh CWT, Tng DJH, Ooi JSG, Yee JX, Chew VSY, Leong YS, Gunasegaran K, Yeo CP, Oon LLE, Sim JXY, Chan KR, Low JG, Ooi EE. Med. PubMed ID: 37105176